T-cube Bispecific Antibody Platform: MOA

A 3D animation showcasing T-cube bispecific antibody platform and its innovative approach to cancer immunotherapy through precise CD137-mediated T-cell activation.

Message

Precision-Targeted Cancer Immunotherapy

This mechanism of action (MOA) animation showcases AP Biosciences’ T-cube bispecific antibody platform technology. The platform features a modular design that enables rapid development of therapeutic solutions for different cancer types. We transformed complex immunotherapy concepts into intuitive visual storytelling—from antibody binding with T-cells and tumor cells, CD137 trimer formation, to precision activation mechanisms within the tumor microenvironment, helping audiences understand how T-cube activates T-cells while avoiding cytokine storms.

Client

AP Biosciences

Services

3D Medical Animation

About the Science

CD137 Clustering

T-Cube bispecific antibodies can connect both T cells and tumor cells. After binding, individual antibodies attract each other and cluster into trimers, amplifying CD137 signaling and prompting T cells to release cytokines that attack cancer cells. 

Design

Character Design

AP Bio’s bispecific antibody platform is modular—like building blocks that can be assembled, disassembled, and swapped. For our character design, we moved away from traditional antibody shapes and embraced a blocky, LEGO-inspired aesthetic instead.

Outcome

This animation helped AP Biosciences win the “Emerging Company of the Year” award at the 2025 Taiwan BIO Awards. Organized by the Taiwan Bio Industry Organization, this honor recognizes biotech companies with exceptional performance in R&D innovation and industry potential.

English Version
Traditional Chinese Version

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